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pentobarbital will lessen the extent or influence of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.Keep an eye on Carefully (1)pentobarbital will lower the level or effect of fentanyl by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of fentan